Archive for November, 2011

That time of the year…zeitgeist

November 30, 2011

Only the inane cat christmas poster floating around is dumber than this:

no comments...(maybe they made one poster naked)

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Cain is going to hell

November 29, 2011

not “happy” that a good negroe in the GOP sense goes to Hell. But he will.

Ethical populism by a philosopherito.

November 22, 2011

Pete Singer is a guru philosopherito followed and admired by atheists, self appointed skeptics and varieties of thinkers disguised as high octane, high power torque ‘commentators of reality and extra dimensions. He endorses among other, loving and having sex with animals, including cetaceans, if you dont kill them, or, given the size of their appariti you dont get blown in th process of enjoying this transhuman orgasmic experience. Also, he has argued for the equivalent  rights for animals and humans, which is ok to a phylogenetic reasonable point. All this based on a utilitarian, neorationalist, neocapaitalist so called rational-scientific-platform much quoted by Pinker, Dennett, Coyne, eugenics advocates and others. Some called this scientific capitalism.

m. brenner making out with dolly

Some of  his arguments are propounded by others based on legitimate merits having nothing to do with the fact you have to be an atheist to be rational.

 Now he argues for the prohibition of cigarretes; world wide mind you. Again, the thing is here to make it look like a perfectly reasonable rational argument.

MY POINT: this is a moving target. A sitting dead duck. Why? because the tobacco “industry” is-now- an easy target, like the catholic church. They cant put up a fight. Tobacco paid all our alcohol, gambling, sexual perversions and environmental polluting ways. I would argue for a long, long time. Is this good? Not really. Remember Prohibition? Probably not, cause we were not around. But we are all aware of the side effects it produced.

And talking about alcohol: where is the rationalist/atheist outrage for all the alcohol related deaths? And talking about a difficult target: sexual childrens’ assault and abuse, pervasive in this society, and maybe in all, except for what the church did? There have been some worrisome articles looking for a evodevo side to pedophilia (the greeks did it, the turks are all faggots, 20 % of children are sexually assaulted in the USA).

Singer comes out as an opportunistic philosopherito. As many rationalist/atheists are. Opportunistic: I stand by it. To end poverty donate he contends. Donate to the highly efficient agencies (sic) doing the work. What about getting directly engaged. In the USA first, not in Burundi to adopt a child ala Jolie.

FOXnews lies outright. What else is news?

November 20, 2011

I was at the gym yesterday morning and watched, in Foxnews,  an edited video of Obama answering a question at a press conference. I was so mad. The edited video left the impression Obama was calling americans lazy. Which is true anyways.

This is the actual trancript:

“QUESTION: I think one related question, looking at the world from the Chinese side, is what they would characterize as impediments to investment in the United States. And so that discussion I’m sure will be part of whatever dialogue you have. And so how are you thinking about that? OBAMA: Well, this is an issue, generally. I think it’s important to remember that the United States is still the largest recipient of foreign investment in the world. And there are a lot of things that make foreign investors see the U.S. as a great opportunity — our stability, our openness, our innovative free market culture. But we’ve been a little bit lazy, I think, over the last couple of decades. We’ve kind of taken for granted — well, people will want to come here and we aren’t out there hungry, selling America and trying to attract new business into America. And so one of things that my administration has done is set up something called SelectUSA that organizes…”

STOP LYING…..Perry, Romney, Gingrich….stop lying…

Futbole for quadriplegics in Rio

November 20, 2011

Ian Sample, at the Guardian yesterday brings this extraordinary news:

“Miguel Nicolelis, a neuroengineer at Duke University Medical Center in Durham, North Carolina, will be watching the opening ceremony of the Brazilian World Cup in 2014 more closely than anyone. Amid the spectacle of the event that will draw millions of viewers around the world will be a very public unveiling of his greatest work.

golgolgoglgolllllllllllllllllllllllllllllllll

One of the highlights of the ceremony will see the Brazilian team walk on to the pitch for the first time in the tournament, striding out behind two quadriplegic teenagers. Nicolelis then wants the teenagers, wearing exoskeletons controlled by his technology, to approach and kick the ball.”

I hope it happens. http://www.nicolelislab.net/ link to Miguels’ lab at Duke. Guessed: Miguel is brasileiro.

Daniel Sada, mexican writer, poet and else is dead

November 19, 2011

Daniel Sada, who wanted to die ‘confused”, in peace and with no pain is gone. He was his own mise en abime, amply used in his work. I wish him the best in his new undertakings. A tu salud danny boy!!!!

I have special affection to him, because his ‘Luces artificiales’ were made as EL GUAPO, a great cultish movie (2007) directed by Marcel Sisniega, whom among other things is a chess grandmaster.

Prediction day

November 18, 2011

UPDATE: Cain will blame his wife and remain toasted. Perry is AWOL. Enjoy it why it last Newt Leroy (Newt? Leroy?)

Humans always coming up with new moves, gambits and manouevers.

Cain and Perry are toasted. Cain more than Perry. Sandusky is a pervert. Gingrich is gonna crush and burn: he wont resist the Fredie Mac deal, what a liar. He deserves Calista. Sexual assault of children is a widespread phenomenon in this society, not only circumscribed to the churches. Raping women in the military has been a cover up for a long time

Schizo and other maladies.

November 18, 2011

StacyMoran at Eureka: “Recent studies have identified common genetic mutations conferring modest risk and rare variants comprising significant risk. One example of a rare cause of psychiatric disorders is the Disrupted in Schizophrenia-1 (DISC1) gene, first identified in a large Scottish pedigree displaying schizophrenia, bipolar disorder and depression.” 

The paper:

Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development. Karun K. Singh, Gianluca De Rienzo, Laurel Drane, Yingwei Mao, Zachary Flood, Jon Madison, Manuel Ferreira, Sarah Bergen, Cillian King, Pamela Sklar, Hazel Sive, Li-Huei Tsai. Neuron 72: 545. Nov 17. 2011.

 “Wnt Signaling, DISC1, and Psychiatric Disorders: Our current and previous work (Mao et al., 2009) suggest a prominent role for DISC1 in regulating the Wnt signaling pathway during brain development. Given that our data suggest that specific human DISC1 variants affect Wnt signaling and brain development, this pathway may indeed play a significant role in psychiatric disorders. This is particularly interesting given that a common mood stabilizer, lithium, is a known GSK3β inhibitor ( [Beaulieu et al., 2008] and [Harwood, 2005] ) and can directly activate Wnt-TCF/LEF gene transcription (Stambolic et al., 1996). Furthermore, some of the recently identified genetic susceptibility factors also fall within the Wnt signaling pathway, directly and indirectly. For example, the Akt gene, which can directly regulate GSK3β activity and downstream TCF/LEF signaling, is itself a schizophrenia risk gene and has been shown to be downregulated in postmortem brains of schizophrenia patients (Emamian et al., 2004). In addition, one of the critical-domain genes in the

despair of not belonging

schizophrenia risk-associated 1q21.1 copy number variation (CNV) is B cell lymphoma 9 (Bcl9), which is required for shuttling and keeping β-catenin within the nucleus in response to Wnt stimulation ( [Consortium, 2008] , [Kramps et al., 2002] and [Stefansson et al., 2008] ). Interestingly, a recent study from the Nestler laboratory has shown that Wnt/GSK3β signaling is important in a mouse model of depression (Wilkinson et al., 2011). This collective data suggest that Wnt/GSK3β signaling is important in mediating mood and psychiatric disorders and may represent at least one pathogenic signaling pathway. In conclusion, our data demonstrate that rare and common DISC1 variants impact Wnt signaling in different model systems to ultimately impair brain development. These data provide a framework from which to explain previously reported associations between common DISC1 variants and human brain structural changes and psychiatric phenotypes. Given that future studies will begin to provide sequencing data for genes that regulate Wnt signaling and brain development, it will be critical to understand how DISC1 variants interact with these genes and how these interactions influence risk for psychiatric disorders.”

good luck

Obama kisses Chavez

November 16, 2011

I am not sure whether this is really dumb or really great. Benetton unleashed their unhate campaign. It is not really cool cause these are some ugly dudes.

mm..venezuelan toothpaste..?

Zuckerberg is a moron

November 14, 2011

I watched M Zuckerberg interviewed by ah Charlie Rose: he is a total idiot. I kinda of believe the Periwinkle twins now. For what I care about facebook.